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Henry Masur, MD; Jonathan E. Kaplan, MD

JAMA. 2009;301(22):2378-2380.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The year 2009 marks the 21st anniversary of the first meeting to draft an AIDS management guideline for prophylaxis against Pneumocystis carinii pneumonia in persons with human immunodeficiency virus (HIV) infection.¹ In 1988, knowledge about HIV/AIDS was rapidly increasing, but relevant publications were appearing in a wide array of journals that clinicians could not easily track, and practitioners articulated a need to have a concise, reliable summary of "best practices."

The initial guidelines were developed by a group of experts from the major AIDS care centers in the United States, who reviewed the literature, debated the issues in a 2-day meeting, provided evidence-based recommendations, and promptly published their guidelines.¹ Subsequently, these guidelines were broadened to include prevention and treatment of other opportunistic infections in HIV-infected adults and children.^2-8 As clinicians and publishers became more comfortable using Web-based resources, these guidelines were posted on . . . [Full Text of this Article]

Author Affiliations: National Institutes of Health, Bethesda, Maryland (Dr Masur); and Centers for Disease Control and Prevention, Atlanta, Georgia (Dr Kaplan).

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