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Smoking as a Factor in Causing Lung Cancer
Commentary by Peter B. Bach, MD, MAPP
JAMA. 2009;301(5):539-541.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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SUMMARY OF THE ORIGINAL ARTICLE
Tobacco Smoking as a Possible Etiologic Factor in Bronchiogenic Carcinoma: A Study of Six Hundred and Eighty-Four Proved Cases
Ernest L. Wynder and Evarts A. Graham, MD
JAMA. 1950;143(4):329-336.
In this case-control study, the investigators compared the smoking histories of individuals with lung cancer and without lung cancer. Participants were matched for age and several dimensions of smoking history were ascertained through a standardized set of questionnaires (including age at initiation and cessation, and average amount smoked per day of cigarettes, cigars, or with a pipe). Each individual's occupational history and history of prior lung disease was captured to control for possible confounders. The investigators found that individuals with lung cancer had a more extensive smoking history than individuals without lung cancer.
See PDF for full text of the original JAMA article.
In 1950, when Wynder and . . . [Full Text of this Article] Epidemiologic Context
Author Affiliation: Health Outcomes Research Group, Memorial Sloan-Kettering Cancer Center, New York, New York.
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