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To the Editor: Atopic eczema (AE, also known as atopic dermatitis) is the most prevalent chronic inflammatory condition in children.¹ The prevalence of AE at age 6 years reaches 20% in Western countries.¹ The typical itchy lesions may cause substantial psychosocial impairment and are a leading cause of sleep loss in childhood.² Approximately every third child with AE develops asthma or allergic rhinitis.¹

Attention-deficit/hyperactivity disorder (ADHD) is the most frequent psychiatric disorder in childhood, with a worldwide prevalence greater than 5%, and imposes a significant economic burden.^3-4 Higher prevalence rates of asthma in children with ADHD suggested a common etiology, but further research failed to identify any substantial pathophysiological relationship.⁵ However, previous studies did not control for AE as a possible confounding factor. We examined the relationship of AE with ADHD in a population-based sample, hypothesizing that AE is a potential cause or exacerbation factor of ADHD symptoms.

Methods

We performed . . . [Full Text of this Article]

Jochen Schmitt, MD, MPH
jochen.schmitt@uniklinikum-dresden.de
Department of Dermatology
Medical Faculty Carl Gustav Carus
Technische Universität Dresden
Dresden, Germany

Marcel Romanos, MD
Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy
Hospital Clinic of the University of Wuerzburg
Wuerzburg, Germany

Natalie M. Schmitt, MD, MPH
Institute of Clinical Pharmacology

Michael Meurer, MD
Department of Dermatology

Wilhelm Kirch, MD
Institute of Clinical Pharmacology
Medical Faculty Carl Gustav Carus
Technische Universität Dresden

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