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	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

To the Editor: In the study of the association between tamsulosin and ophthalmic adverse events following cataract surgery by Dr Bell and colleagues,¹ I believe there is a contradiction between the results as presented in the abstract and in the body of the article. The abstract states, "Adverse events were significantly more common among patients with recent tamsulosin exposure (7.5% vs 2.7%; adjusted odds ratio [OR], 2.33; 95% confidence interval [CI], 1.22-4.43). . . . " This suggests a comparison of measurement of adverse outcomes between exposed vs nonexposed patients.

However, the nested case-control design of the study does not allow such an inference. As correctly stated in the "Results" section of the article, "In our primary analysis of adverse events following cataract surgery, 21 case patients (7.5%) and 30 control patients (2.7%) received tamsulosin in the 14 days before surgery. This resulted in an adjusted OR of 2.33 (95% CI, 1.22-4.43 . . . )".

When considering . . . [Full Text of this Article]

Sergio Ponce-de-Leon, MD
splr55@gmail.com
Clinical Epidemiology Unit
Instituto Nacional de Ciencias Medicas y Nutricion
Mexico City, Mexico

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RELATED ARTICLE

Association Between Tamsulosin and Serious Ophthalmic Adverse Events in Older Men Following Cataract Surgery
Chaim M. Bell, Wendy V. Hatch, Hadas D. Fischer, Geta Cernat, J. Michael Paterson, Andrea Gruneir, Sudeep S. Gill, Susan E. Bronskill, Geoffrey M. Anderson, and Paula A. Rochon
JAMA. 2009;301(19):1991-1996.
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RELATED LETTERS

Tamsulosin and Ophthalmic Adverse Events After Cataract Surgery
Bruce I. Gaynes
JAMA. 2009;302(10):1055.
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Tamsulosin and Ophthalmic Adverse Events After Cataract Surgery—Reply
Chaim Bell, Andrea Gruneir, and Paula Rochon
JAMA. 2009;302(10):1055.
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