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  Vol. 302 No. 11, September 16, 2009 TABLE OF CONTENTS
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  From the Centers for Disease Control and Prevention: Morbidity and Mortality Weekly Report
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Evaluation of Rapid Influenza Diagnostic Tests for Detection of Novel Influenza A (H1N1) Virus—United States, 2009

JAMA. 2009;302(11):1163-1164.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

MMWR. 2009;58:826-829

2 tables omitted

The recent appearance and worldwide spread of novel influenza A (H1N1) virus1,2 has highlighted the need to evaluate commercially available, widely used, rapid influenza diagnostic tests (RIDTs) for their ability to detect these viral antigens in respiratory clinical specimens. As an initial assessment, CDC conducted an evaluation of multiple RIDTs. Sixty-five clinical respiratory specimens collected during April-May 2009* that had previously tested positive either for novel influenza A (H1N1) or for seasonal influenza A (H1N1) or A (H3N2) viruses by real-time reverse transcription–polymerase chain reaction (rRT-PCR) assay were used in the evaluation. The results showed that, although the RIDTs were capable of detecting novel A (H1N1) virus from respiratory specimens containing high levels of virus (as indicated by low cycle threshold [Ct] values), the overall sensitivity was low (40%-69%) among all specimens tested and declined substantially as virus levels decreased (and Ct values increased). These . . . [Full Text of this Article]

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