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  Vol. 302 No. 4, July 22/29, 2009 TABLE OF CONTENTS
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New Therapies for GI Cancers Fall Short

Tracy Hampton, PhD

JAMA. 2009;302(4):373-374.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Results from several large clinical trials on cancers of the colon, rectum, and anus have failed to fulfill hopes for better treatments. Findings presented at the 45th Annual Meeting of the American Society of Clinical Oncology (ASCO), held May 29 through June 2 in Orlando, indicate that in most cases, the current standards of care should remain the treatments of choice. However, one potentially practice-changing trial suggested that many patients with advanced colorectal cancer can forgo standard surgery and receive chemotherapy as first-line care.


Figure 90070FA
Chemotherapy should replace surgery as initial treatment for many patients with certain types of colorectal cancer, according to clinical trials. (Photo credit: David M. Martin, MD/www.sciencesource.com)

"These large, conclusive trials tell us what works, and importantly, tell us what doesn't work," said Nicholas Petrelli, MD, medical director of the Helen F. Graham Cancer Center in Wilmington, Del, who was not involved . . . [Full Text of this Article]

NO MORE SURGERY



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