This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Related article  • Related letters  • Similar articles in JAMA  Topic Collections  • Neurology  • Cardiovascular System  • Diagnosis  • Prognosis/ Outcomes  • Cardiovascular Disease/ Myocardial Infarction  • Endocrine Diseases  • Diabetes Mellitus  • Alert me on articles by topic  Social Bookmarking   What's this?

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

To the Editor: Dr Young and colleagues¹ reported the results of the Detection of Ischemia in Asymptomatic Diabetics (DIAD) study. This trial addressed whether routine screening of patients with asymptomatic type 2 diabetes for coronary artery disease (CAD) with myocardial perfusion imaging (MPI) is warranted. Among 1123 patients, the primary outcome of cardiac death or nonfatal myocardial infarction occurred in 15 patients in the screening group and in 17 patients in the no-screening group during the mean follow-up of 4.8 years (P = .73). The low-risk nature of the study population is one possible explanation for the negative results of the DIAD study, which had a low rate of high-risk MPI results and low cardiac event rates. However, in a clinical practice setting the presence of advanced CAD in asymptomatic diabetic patients is common, and the prognosis of patients with type 2 diabetes is poor.²

The identification of a higher-risk . . . [Full Text of this Article]

Taishiro Chikamori, MD
chikamd@tokyo-med.ac.jp
Department of Cardiology
Tokyo Medical University
Tokyo, Japan

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLE

Cardiac Outcomes After Screening for Asymptomatic Coronary Artery Disease in Patients With Type 2 Diabetes: The DIAD Study: A Randomized Controlled Trial
Lawrence H. Young, Frans J. Th. Wackers, Deborah A. Chyun, Janice A. Davey, Eugene J. Barrett, Raymond Taillefer, Gary V. Heller, Ami E. Iskandrian, Steven D. Wittlin, Neil Filipchuk, Robert E. Ratner, Silvio E. Inzucchi, and for the DIAD Investigators
JAMA. 2009;301(15):1547-1555.
ABSTRACT | FULL TEXT  

RELATED LETTERS

Screening for Asymptomatic Coronary Artery Disease in Patients With Type 2 Diabetes
Aaron I. Vinik and Raelene E. Maser
JAMA. 2009;302(7):735-736.
EXTRACT | FULL TEXT  

Screening for Asymptomatic Coronary Artery Disease in Patients With Type 2 Diabetes
Mladen I. Vidovich
JAMA. 2009;302(7):736.
EXTRACT | FULL TEXT  

Screening for Asymptomatic Coronary Artery Disease in Patients With Type 2 Diabetes—Reply
Frans J. Th. Wackers and Lawrence H. Young
JAMA. 2009;302(7):736-737.
EXTRACT | FULL TEXT