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To the Editor: Dr Young and colleagues¹ reported on cardiac outcomes in patients with diabetes after screening with MPI. The article did not include information regarding the radiation dose given to the patients in the screening group.

A recent study by Hausleiter et al² underscored complacence with the issue of radiation dose. Radiation dose is cumulative, and over years patients with cardiac disease may be exposed not only to radiation from computed tomography but also to nuclear medicine examinations, coronary angiography/angioplasty, and electrophysiology procedures, which can increase lifetime risk of cancer.³ Unfortunately, even in contemporary studies radiation dose is not routinely reported.

Financial Disclosures: None reported.

Mladen I. Vidovich, MD
miv@uic.edu
Department of Medicine
University of Illinois at Chicago

1. Young LH, Wackers FJ, Chyun DA; et al, DIAD Investigators. Cardiac outcomes after screening for asymptomatic coronary artery disease in patients with type 2 diabetes: the DIAD study: a randomized controlled trial. JAMA. 2009;301(15):1547-1555. FREE FULL TEXT 2. Hausleiter J, Meyer T, Hermann F; et al. Estimated radiation dose associated with cardiac CT angiography. JAMA. 2009;301(5):500-507. FREE FULL TEXT 3. Einstein AJ, Henzlova MJ, Rajagopalan S. Estimating risk of cancer associated with radiation exposure from 64-slice computed tomography coronary angiography. JAMA. 2007;298(3):317-323. FREE FULL TEXT

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2009;302(7):736.

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Cardiac Outcomes After Screening for Asymptomatic Coronary Artery Disease in Patients With Type 2 Diabetes: The DIAD Study: A Randomized Controlled Trial
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