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JAMA. 1999;282:1689-1690.

Physicians in the United States, Canada, and Mexico
Physicians with current and valid licenses in the United States, Canada, or Mexico who read any 3 of the selected continuing medical education (CME) articles in this issue of JAMA, complete the CME Evaluation Form, and fax it to the number or mail it to the address at the bottom of the CME Evaluation Form are eligible for category 1 CME credit. There is no charge.

The American Medical Association (AMA) is accredited by the Accreditation Council for Continuing Medical Education to sponsor CME for physicians. The AMA designates this educational activity for up to 1 hour of category 1 CME credit per JAMA issue toward the AMA Physician's Recognition Award (PRA). Each physician should claim for credit only those hours that were actually spent in this educational activity.

Physicians in Other Countries
Physicians with current and valid licenses in the United States, Mexico, or Canada are eligible for CME credit even if they live or practice in other countries. Physicians licensed in other countries are also welcome to participate in this CME activity. However, the PRA is available only to physicians licensed in the United States, Canada, or Mexico.

Earning Credit and the CME Evaluation Form
To earn credit, read 3 of the articles listed below that are designated for CME credit carefully and complete the CME Evaluation Form. The CME Evaluation Form must be submitted within 1 month of the issue date. A certificate awarding 1 hour of category 1 CME credit will be faxed or mailed to you; it is then your responsibility to maintain a record of credit received.

One of our goals is to assess continually the educational needs of our readers so we may enhance the educational effectiveness of JAMA. To achieve this goal, we need your help. You must complete the CME Evaluation Form to receive credit.

Statement of Educational Purpose
JAMA is a general medical journal. Its mission and educational purpose is to promote the science and art of medicine and the betterment of the public health. A flexible curriculum of article topics is developed annually by THE JOURNAL's editorial board and is then supplemented throughout the year with information gained from readers, authors, reviewers, and editors. To accommodate the diversity of practice types within JAMA's readership, the Reader's Choice CME activity allows readers, as adult learners, to determine their own educational needs and to assist the editors in addressing their needs in future issues.

Readers of JAMA should be able to attain the following educational objectives: (1) select and read at least 3 articles in 1 issue to gain new medical information on topics of particular interest to them as physicians, (2) assess the articles' value to them as practicing physicians, and (3) think carefully about how this new information may influence their own practices. The educational objective for each CME article is given after the article title below.

CME Articles in This Issue of JAMA
The following articles in this issue may be read for CME credit:

Residual HIV-1 RNA in Blood Plasma of Patients Taking Suppressive Highly Active Antiretroviral Therapy (SEE ARTICLE)

Educational Objective: To learn that antiretroviral therapy may not ablate HIV-1 replication.

Discontinuation of Anticytomegalovirus Therapy in Patients With HIV Infection and Cytomegalovirus Retinitis (SEE ARTICLE)

Educational Objective: To learn that anti-CMV medications may be safely stopped in some patients with stable CMV retinitis receiving antiretroviral therapy.

Evaluation of Prognostic Criteria for Determining Hospice Eligibility in Patients With Advanced Lung, Heart, or Liver Disease (SEE ARTICLE)

Educational Objective: To understand the predictive value of hospice eligibility criteria.

Placental Abruption and Adverse Perinatal Outcomes (SEE ARTICLE)

Educational Objective: To understand effects on perinatal outcomes by extent of placental separation.

Adverse Childhood Experiences and Smoking During Adolescence and Adulthood (SEE ARTICLE)

Educational Objective: To learn that adverse childhood experiences may increase the risk of adolescent smoking.

Alterations in Liver ATP Homeostasis in Human Nonalcoholic Steatohepatitis: A Pilot Study (SEE ARTICLE)

Educational Objective: To learn that progression of nonalcoholic steatohepatitis may be related to altered hepatic energy homeostasis.

After reading 3 of these articles, complete the CME Evaluation Form.

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Residual HIV-1 RNA in Blood Plasma of Patients Taking Suppressive Highly Active Antiretroviral Therapy
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JAMA. 1999;282(17):1627-1632.
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Discontinuation of Anticytomegalovirus Therapy in Patients With HIV Infection and Cytomegalovirus Retinitis
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Adverse Childhood Experiences and Smoking During Adolescence and Adulthood
Robert F. Anda, Janet B. Croft, Vincent J. Felitti, Dale Nordenberg, Wayne H. Giles, David F. Williamson, and Gary A. Giovino
JAMA. 1999;282(17):1652-1658.
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Alterations in Liver ATP Homeostasis in Human Nonalcoholic Steatohepatitis: A Pilot Study
Helena Cortez-Pinto, John Chatham, V. P. Chacko, Cheryl Arnold, Asif Rashid, and Anna Mae Diehl
JAMA. 1999;282(17):1659-1664.
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