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Factors Considered Important at the End of Life by Patients, Family, Physicians, and Other Care Providers
Karen E. Steinhauser, PhD;
Nicholas A. Christakis, MD, PhD, MPH;
Elizabeth C. Clipp, PhD, MS, RN;
Maya McNeilly, PhD;
Lauren McIntyre, PhD;
James A. Tulsky, MD
JAMA. 2000;284:2476-2482.
ABSTRACT
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Context A clear understanding of what patients, families, and health care practitioners view as important at the end of life is integral to the success of improving care of dying patients. Empirical evidence defining such factors, however, is lacking.
Objective To determine the factors considered important at the end of life by patients, their families, physicians, and other care providers.
Design and Setting Cross-sectional, stratified random national survey conducted in March-August 1999.
Participants Seriously ill patients (n = 340), recently bereaved family (n = 332), physicians (n = 361), and other care providers (nurses, social workers, chaplains, and hospice volunteers; n = 429).
Main Outcome Measures Importance of 44 attributes of quality at the end of life (5-point scale) and rankings of 9 major attributes, compared in the 4 groups.
Results Twenty-six items consistently were rated as being important (>70% responding that item is important) across all 4 groups, including pain and symptom management, preparation for death, achieving a sense of completion, decisions about treatment preferences, and being treated as a "whole person." Eight items received strong importance ratings from patients but less from physicians (P<.001), including being mentally aware, having funeral arrangements planned, not being a burden, helping others, and coming to peace with God. Ten items had broad variation within as well as among the 4 groups, including decisions about life-sustaining treatments, dying at home, and talking about the meaning of death. Participants ranked freedom from pain most important and dying at home least important among 9 major attributes.
Conclusions Although pain and symptom management, communication with one's physician, preparation for death, and the opportunity to achieve a sense of completion are important to most, other factors important to quality at the end of life differ by role and by individual. Efforts to evaluate and improve patients' and families' experiences at the end of life must account for diverse perceptions of quality.
INTRODUCTION
Dying patients confront complex and unique challenges that threaten their physical, emotional, and spiritual integrity. The Study to Understand Prognosis and Preferences for Outcomes and Risks of Treatments (SUPPORT) documented that many patients die prolonged and painful deaths, receiving unwanted, expensive, and invasive care.1 Patients' emotional suffering at the end of life can be profound, yet physicians are too frequently ill equipped to address this suffering.2-3 In response, medical societies, health care organizations, and the public have identified improved end-of-life care as a high national priority. The American Medical Association and the Institute of Medicine have outlined goals for improved care of the dying, and The Robert Wood Johnson Foundation has devoted millions of dollars to public education on this issue through the Last Acts initiative.4-6
These efforts depend, in part, on certain presumptions regarding how dying patients and their families define quality at the end of life. During the latter part of the 20th century, advances in biomedical technology propelled us to see a "good" death as one involving the fight against disease. Partly in response to this view, the modern hospice movement emerged, redefining a good death as one that included acceptance and closure, most often at home. Unfortunately, empirical support for a notion of a good death that might best structure end-of-life care is lacking, as is a comprehensive understanding about how the definition of a good death might vary across relevant constituencies.
Empirical evidence defining a good death would assist efforts to improve end-of-life care by documenting the breadth of preferences of dying patients and their families. Such data would provide clinicians with information to help guide patients through this challenging and uncertain time. Therefore, we investigated what patients, family members, physicians, and others consider to be important attributes at the end of life.
METHODS
This study was a cross-sectional, stratified random national survey of seriously ill patients, recently bereaved family members, physicians, and other care providers (nurses, social workers, chaplains, and hospice volunteers).
Subjects
Patients were randomly selected from the national Veterans Affairs (VA) Patient Treatment File database using International Classification of Diseases, Ninth Revision diagnostic codes for a variety of advanced chronic illnesses (lung, colon, gastric, esophageal, pancreatic, head and neck, and lymphatic cancer; end-stage renal disease; advanced chronic obstructive pulmonary disease; and congestive heart failure). All patients had been hospitalized for these diagnoses within the prior year. Family members were randomly selected from national samples of relatives of VA patients who had died 6 months to 1 year earlier. We chose this period so that family members would be past the immediate stages of grief, yet the death would not be so distant that the risk of retrospective bias would be introduced.7-10 Patient and family samples reflected the racial/ethnic and socioeconomic composition of VA patients. However, we oversampled female patients (20%).
Individuals involved in end-of-life care were randomly selected from membership lists of national professional associations (American College of Physicians–American Society of Internal Medicine, American Nurses Association, National Association of Social Workers, Association of Professional Chaplains, and National Hospice Volunteers). The sample composition reflects the demographic profile of each association's membership.
We mailed surveys to 500 subjects from each of the 4 groups (total potential n = 2000). Sample size was calculated to provide adequate power to detect differences among groups. We used several well-established techniques to maximize response rates and data quality.11-12 Participants who did not respond to the initial survey within 5 weeks received a second survey that included return postage. In the first wave only, we provided a nominal financial incentive. Survey completion time was less than 15 minutes. The institutional review boards of the Durham VA and Duke University Medical Centers, Durham, NC, approved the study.
Measurements
The survey asked respondents to rate the importance of 44 attributes of experience at the end of life (survey available at http://hsrd.durham.med.va.gov/pmepc/Program.html). Survey items were generated on the basis of 12 previously conducted focus groups and in-depth interviews with patients, family members, physicians, and other care providers in which participants were asked to define attributes of a good death.13 Participants rated the importance of each item on a 5-point scale: strongly disagree, disagree, neither agree nor disagree, agree, and strongly agree. Respondents also were presented with the 9 items most frequently identified in the focus groups and asked to rank-order them from 1 (most important) to 9 (least important). The rank sum for each respondent for the 9 items was constrained to be 45; tied ranks were permitted.
Analysis
We examined the distribution of responses for all 44 items, including frequency, mean, median, and range. For descriptive parsimony, we collapsed the 5 response categories into 3: agree, disagree, and neither agree nor disagree. Based on natural breaks in the distribution of the data, items for which more than 70% of respondents in all 4 groups chose "agree" or "strongly agree" were identified as having substantial agreement. We used  2 and, when appropriate, Fisher exact tests of independence to compare responses among groups. We also assessed mean rank score for the 9 ranked items and conducted Friedman tests to examine whether rankings within groups were different than would be expected by chance alone. Wilcoxon tests were used to examine the significance of specific response differences among groups.
To identify independent correlates of 4 selected attributes with the most varied ratings of importance, we conducted multivariate exploratory analyses of factors associated with item response. We used logistic regression to model the likelihood of responding "disagree" or "neither agree nor disagree" vs "agree" for a given item. We used a stepwise procedure to identify covariates strongly associated with response. Our final models also included variables in which we had a substantive interest, regardless of their precise significance level. Each question was initially evaluated in the pooled sample using the same set of covariates. We present odds ratios (ORs) and 95% confidence intervals (CIs) only for significant covariates. Because income and education were strongly associated with role, socioeconomic status effects on the full sample could not be evaluated; hence, the effects of income and education on patient and bereaved family member responses were tested in separate analyses. Exploratory analyses revealed no differences in patients' responses by diagnosis; therefore, it was excluded from the multivariate models. Because only female patients were oversampled, we present results of unweighted analyses. In analyses not shown, we also modeled items as a 3-category response variable, using multinomial logistic regression. Because the results were nearly identical, we report the less cumbersome binary models. Statistical analyses were conducted using SAS Version 8.0 software (SAS Institute Inc, Cary, NC).
RESULTS
Of the 2000 mailed surveys, 1885 potential subjects could be reached (ie, had not moved or died). We received responses from 340 (77%) of 444 patients, 332 (71%) of 465 bereaved family members, 361 (74%) of 486 physicians, and 429 (88%) of 490 other care providers(120 chaplains [96%], 105 hospice volunteers [84%], 107 social workers [86%], and 97 nurses [78%]), for a total of 1462 participants. The average age of respondents was 57 years; 51% were men and 82% were white (Table 1). Nonrespondents did not differ from respondents with regard to sex, race/ethnicity, diagnosis, or geographic location.
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Table 1. Demographics of Survey Participants*
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Ratings of Attribute Importance
Based on responses to the survey, we classified the 44 attributes into 3 categories: (1) items with strong agreement regarding importance among the entire sample (>70% of every group agreed that the attribute is important); (2) items with strong agreement regarding importance (>70%) among patients but less agreement among physicians; and (3) items with broad response variation among the entire sample (ie, large percentages of respondents agreeing, disagreeing, and neither agreeing nor disagreeing that the item is important).
Attributes Rated As Important Among All Participants. Twenty-six survey items displayed strong agreement in all 4 groups (Table 2). Of the 26 items, 5 were associated with symptoms or personal care: freedom from pain, freedom from anxiety, freedom from shortness of breath, being kept clean, and having physical touch. Four items related to preparation for the end of life: having financial affairs in order, feeling prepared to die, believing that one's family is prepared for one's death, and knowing what to expect about one's physical condition. Three items related to achieving a sense of completion about one's life: saying good-bye to important people, remembering personal accomplishments, and resolving unfinished business. Two items involved decisions about treatment preferences: having treatment preferences in writing and naming someone to make decisions in the event that one cannot. Seven items were associated with what focus group participants in a prior study13 called "being treated as a whole person": maintaining one's dignity, maintaining a sense of humor, having a physician who knows one as a whole person, presence of close friends, not dying alone, and having someone who will listen. Finally, 5 items were linked to patients' relationships with health care professionals: receiving care from one's personal physician, trusting one's physician, having a nurse with whom one feels comfortable, knowing that one's physician is comfortable talking about death and dying, and having a physician with whom one can discuss personal fears.
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Table 2. Attributes Rated as Important by More Than 70% of All Participants
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Attributes Important Among Patients. The second category included 8 items that were consistently rated as important among patients (>70%) but were significantly less important to physicians (P<.001) (Table 3). These included being mentally aware, having funeral arrangements planned, feeling that one's life was complete, not being a burden to family or society, being able to help others, coming to peace with God, and praying. These differences persisted after conducting multivariate analyses controlling for sex, race/ethnicity, socioeconomic status, household composition, religion, and religiosity (data available on request).
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Table 3. Attributes Rated as Important by More Than 70% of Patients But Not Physicians*
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Attributes With Broad Response Variation Among All Participants. A final category comprised 10 items with a broad distribution of responses among the 4 groups. These items included attributes relating to treatment preferences, preparation, and completion or spirituality (Table 4). For example, the groups showed wide response variation regarding the importance of knowing the timing of death. A slight majority of the sample agreed with the importance of meeting with a clergy member, having a chance to talk about the meaning of death, and discussing spiritual beliefs with one's physician. However, a sizable percentage of each group disagreed or neither agreed nor disagreed about the importance of these items (Table 4). Compared with patients, bereaved family members more frequently agreed with and physicians less frequently agreed with the importance of meeting with clergy.
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Table 4. Attributes With Broad Variation Among Participants Regarding Importance at End of Life
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Multivariate Analyses
Multivariate models were created controlling for role, sex, race/ethnicity, income, education, religion, religiosity, being present during the last hour of someone's life, household composition, self-reported health status, and, for patients, diagnosis. Only ORs that were significant are presented herein.
Use of All Available Treatments. Physicians (OR, 0.1; 95% CI, 0.1-0.2) and other care providers (OR, 0.08; 95% CI, 0.04-0.14) were significantly less likely than patients to agree with the importance of using all available treatments no matter what the chance of recovery, whereas bereaved family members were equally likely to agree (OR, 0.8; 95% CI, 0.6-3.3). African American (OR, 3.3; 95% CI, 2.0-4.0) and other nonwhite ethnic groups (OR, 2.5; 95% CI, 1.4-3.3) were significantly more likely than white participants to agree with the importance of using all available treatments. Persons who had not been present during the last hour of another person's life were also more likely to agree (OR, 1.7; 95% CI, 1.0-2.5). Sex, religion, and the other variables were not associated with the response to this question. Among patients and bereaved family members, respondents with more education (bachelor's degree, OR, 0.5; 95% CI, 0.3-0.8; graduate/professional degree, OR, 0.4; 95% CI, 0.2-0.9 vs no college) and higher annual income ($20,000–$40,000, OR, 1.0; 95% CI, 0.6-1.7;  $50,000, OR, 0.3; 95% CI, 0.2-0.8 vs <$20,000) were significantly less likely to agree with the importance of use of all available treatments.
Controlling Time and Place of Death. Religiosity was the only covariate significantly associated with preference for controlling the time and place of death. Participants who considered faith or spirituality not at all important were significantly more likely (OR, 1.7; 95% CI, 1.1-2.0) than were those who considered it very important to agree with the importance of such control.
Dying at Home. Other care providers (OR, 1.7; 95% CI, 1.1-2.0) were significantly more likely to agree with the importance of dying at home compared with patients. Physicians (OR, 1.4; 95% CI, 1.0-2.0) and bereaved family members (OR, 0.8; 95% CI, 0.6-1.3) were not significantly different from patients. Roman Catholic (OR, 1.4; 95% CI, 1.0-2.0) and "other" respondents were significantly less likely than Protestants (the reference point) or Jews (OR, 0.8; 95% CI, 0.5-1.3) to disagree. Separate logistic analyses showed no significant covariates among patients and families.
Talking About the Meaning of Death. Physicians (OR, 2.0; 95% CI, 1.3-2.5), other care providers (OR, 1.7; 95% CI, 1.1-2.0), and bereaved family members (OR, 1.7; 95% CI, 1.1-2.7) were significantly more likely than patients to agree that talking about the meaning of death is important. Those for whom faith or spirituality was not at all (OR, 0.3; 95% CI, 0.2-0.5) or somewhat (OR, 0.4; 95% CI, 0.3-0.6) important were significantly less likely than those for whom spirituality was very important to agree that this attribute was important. Among patients and family members, women were significantly more likely to agree with talking about the meaning of death (OR, 2.0; 95% CI, 1.3-2.5).
Ranking Attributes
We measured the mean rank scores for the 9 preselected attributes, with 1 being most important and 9 being least important (Table 5). Friedman tests were significant (P<.001), suggesting that the rankings by each group were different than would be expected by chance alone. Freedom from pain was ranked as most important (ie, received the lowest mean score) by patients (3.07), bereaved family members (2.99), physicians (2.36), and other care providers (2.83). Coming to peace with God and presence of family were ranked second or third in importance in all groups. For patients and families, the difference between the ranking of freedom from pain and being at peace with God was trivial (0.09 and 0.12 difference, respectively), suggesting that these items are nearly identical in importance for both groups. Physicians' mean score difference between the items was 2.46; other care providers had a difference of 0.88 in mean score (P<.001). Of note, dying at home received the least important relative ranking by all groups except other care providers, who ranked it second to last.
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Table 5. Mean Rank Scores of 9 Preselected Attributes*
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COMMENT
Our results reveal areas of strong agreement and variation among end-of-life care participants' definitions of what constitutes a good death. More than half of the survey items showed consensus among all 4 groups. For example, in concert with previous findings in the palliative care literature, survey participants overwhelmingly endorsed pain and symptom management.14-16 Regardless of role, respondents also converged on the importance of preparation for the end of life. These findings echo the results of a recent study that showed that many patients wish to plan ahead for their own deaths and support the importance of prognostication in clinical practice.17-20 Additionally, respondents expressed a strong preference for having an opportunity to gain a sense of completion in their lives. Life review, saying good-bye, and resolving unfinished business provide both patients and their families with an opportunity for human development at the end of life.21 Finally, all groups advocated strong relationships between patients and health care professionals that emphasized more than just the patient's disease.
Results of this study also highlight one of the challenges of comprehensive end-of-life care: attending to aspects of care that are not intuitively important to clinicians but are critical to patients and their families. For example, in contrast with physicians, patients strongly endorsed the importance of being mentally aware. When forced to choose between attributes (Table 5), patients ranked pain control higher than mental awareness; however, the mean rank difference was only 1.51. In contrast, the average difference between the same items among physicians was 3.76, suggesting physicians may be more willing than patients to sacrifice lucidity for analgesia. Similarly, other care providers generally emphasize what patients need to receive, but our results indicate that being able to help others is central to patients' conceptions of quality at the end of life.13 Finally, patients highly valued attention to spirituality; in particular, the importance of coming to peace with God and praying. Rank-ordered responses showed that coming to peace with God and pain control were nearly identical in importance for patients and bereaved family members.
Perhaps the most interesting findings of our study are items for which there was broad response variation within and across all groups. They serve as a reminder that there is no one definition of a good death; quality end-of-life care is a dynamic process that is negotiated and renegotiated among patients, families, and health care professionals, a process moderated by individual values, knowledge, and preferences for care. We choose to illustrate this point with discussion of 4 critical issues raised in the survey.
Consistent with previous research,22-23 African Americans had higher odds than white participants of wanting all available treatments, which may reflect a preference for life-sustaining treatment or distrust of the predominantly white medical culture.22 The disagreement by physicians and other care providers with use of all available treatments may reflect greater familiarity with life-sustaining treatments. In one study, patients were less likely to want cardiopulmonary resuscitation after receiving additional information about the procedure.24 In addition, despite many patients valuing use of all treatments, most disagreed with the importance of being connected to machines. In contrast, physicians equate these interventions and disagreed with both.
Respondents displayed broad variation in their desire to control time and place of death. Those with less religiosity were most likely to want control.
Given the strong public support for the hospice movement and its emphasis on home care, we expected to find overwhelming preference for dying at home.25 However, fewer than half of all participants in our sample agreed that this was an important attribute in quality of dying. Moreover, dying at home was consistently ranked least in importance among 9 selected attributes. Religion and role were associated with a preference for dying at home. Recently, Fried et al demonstrated a similar preference among older adults.26 The notion of dying at home may be romantic among health care professionals who want to provide a good death. However, as symptoms accelerate in the last 24 to 48 hours, some patients and families may feel overwhelmed by concerns about symptom control or a dead body in the home and, therefore, prefer a skilled care environment.26 Therefore, although for many patients an appropriate goal is to allow them to die at home, this should not be assumed.
While we anticipated that religiosity and female sex would be associated with a desire to talk about the meaning of death, we did not expect that physicians, other care providers, and bereaved family members would be more likely to agree with its importance than were patients. Similarly, patients as a group were least likely to rate discussing personal fears as important. All groups lacked consensus in assigning importance to meeting with clergy and discussing spiritual beliefs with one's physician. Spirituality, however, was clearly important to patients, as illustrated by their strong consensus surrounding the need for coming to peace with God and praying. These findings suggest that for some patients, issues of faith that are resolved with oneself are more important than social or interpersonal expressions of spirituality.27
This study has several limitations. Patients and family members were recruited from VA medical centers; therefore, generalizations to other groups should be made cautiously. However, participants' preferences reflected death in a variety of settings, and patients and families participating in the study represented broad age, educational, and socioeconomic ranges. The individuals comprising other care providers are a diverse group and are not necessarily expected to form a cohesive whole. However, given their role in end-of-life care, it is important to determine their viewpoints, although future studies should evaluate differences within these groups.
CONCLUSIONS
The results of this survey suggest that for patients and families, physical care is expectedly crucial, but is only one component of total care. Whereas physicians tend to focus on physical aspects, patients and families tend to view the end of life with broader psychosocial and spiritual meaning, shaped by a lifetime of experiences. While physicians' biomedical focus is a natural outgrowth of medical care that emphasizes the physical self, physicians should recognize patients' other needs and facilitate means for them to be addressed. Physicians also should recognize that there is no one definition of a good death. Quality care at the end of life is highly individual and should be achieved through a process of shared decision making and clear communication that acknowledges the values and preferences of patients and their families.
Patients, families, and care providers each play a critical role in shaping the experience at the end of life. As our cultural lexicon of death and dying expands, further research is needed to define both the common ground and areas for negotiation as participants gather to construct quality at the end of life. A challenge to medicine is to design flexible care systems that permit a variety of expressions of a good death.
AUTHOR INFORMATION
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Funding/Support: This work was supported by VA Health Services Research and Development grant IIR 96-066. Dr Tulsky is supported by a VA Health Services Research Career Development Award and a Robert Wood Johnson Generalist Physician Faculty Scholars Award. Drs Tulsky and Christakis are Project on Death in America Soros Faculty Scholars.
Disclaimer: The views expressed in this article are those of the authors and do not necessarily represent the views of the Department of Veterans Affairs.
Acknowledgment: We are grateful to Steven C. Grambow, PhD, for his expert and thorough consultation on statistical analyses.
Corresponding Author and Reprints: Karen E. Steinhauser, PhD, Veterans Affairs Medical Center (152), 508 Fulton St, Durham, NC 27705 (e-mail: karensteinhauser{at}mindspring.com).
Author Affiliations: Program on the Medical Encounter and Palliative Care (Drs Steinhauser and Tulsky), Center for Health Services Research in Primary Care (Drs Steinhauser, McIntyre, and Tulsky), and Geriatric Research Education and Clinical Center (Dr Clipp), Durham Veterans Affairs Medical Center, Department of Medicine (Drs Steinhauser, Clipp, and Tulsky), Center for the Study of Aging and Human Development (Drs Steinhauser, Clipp, McNeilly, and Tulsky), and Institute on Care at the End of Life (Dr Tulsky), Duke University, and the Institute for Multiculturalism (Dr McNeilly), Durham, NC; and the Departments of Medicine and Sociology, University of Chicago, Chicago, Ill (Dr Christakis).
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Associations Between End-of-Life Discussions, Patient Mental Health, Medical Care Near Death, and Caregiver Bereavement Adjustment
Wright et al.
JAMA 2008;300:1665-1673.
ABSTRACT
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Preference for place of care and place of death in palliative care: are these different questions?
Agar et al.
Palliat Med 2008;22:787-795.
ABSTRACT
Care for Patients in the Last Months of Life: The Belgian Sentinel Network Monitoring End-of-Life Care Study
Van den Block et al.
Arch Intern Med 2008;168:1747-1754.
ABSTRACT
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An Exploratory Study of Spiritual Care at the End of Life
Daaleman et al.
Ann Fam Med 2008;6:406-411.
ABSTRACT
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Evaluation of End-of-Life Cancer Care From the Perspective of Bereaved Family Members: The Japanese Experience
Miyashita et al.
JCO 2008;26:3845-3852.
ABSTRACT
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Evidence-Based Recommendations for Information and Care Planning in Cancer Care
Walling et al.
JCO 2008;26:3896-3902.
ABSTRACT
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How Can We Make the Pain Go Away? Public Policies to Manage Pain at the End of Life
Imhof and Kaskie
Gerontologist 2008;48:423-431.
ABSTRACT
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The End-of-Life Experience in Long-Term Care: Five Themes Identified From Focus Groups With Residents, Family Members, and Staff
Munn et al.
Gerontologist 2008;48:485-494.
ABSTRACT
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Disclosure of Incurable Illness to Spouses: Do They Want to Know? A Swedish Population-Based Follow-Up Study
Dahlstrand et al.
JCO 2008;26:3372-3379.
ABSTRACT
| FULL TEXT
Differing management of people with advanced cancer and delirium by four sub-specialties
Agar et al.
Palliat Med 2008;22:633-640.
ABSTRACT
"Writing is a way of saying things I can't say"--therapeutic creative writing: a qualitative study of its value to people with cancer cared for in cancer and palliative healthcare
Bolton
Med. Humanities 2008;34:40-46.
ABSTRACT
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The Japan HOspice and Palliative Care Evaluation Study (J-HOPE Study): Study Design and Characteristics of Participating Institutions
Miyashita et al.
AM J HOSP PALLIAT CARE 2008;25:223-232.
ABSTRACT
A Family's Request for Complementary Medicine After Patient Brain Death
Applbaum et al.
JAMA 2008;299:2188-2193.
ABSTRACT
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Prediction of Patient Survival by Healthcare Professionals in a Specialist Palliative Care Inpatient Unit: A Prospective Study
Twomey et al.
AM J HOSP PALLIAT CARE 2008;25:139-145.
ABSTRACT
"What Bothers You the Most?" Initial Responses From Patients Receiving Palliative Care Consultation
Shah et al.
AM J HOSP PALLIAT CARE 2008;25:88-92.
ABSTRACT
Circumstances of Death in Hospitalized Patients and Nurses' Perceptions: French Multicenter Mort-a-l'Hopital Survey
Ferrand et al.
Arch Intern Med 2008;168:867-875.
ABSTRACT
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Effectiveness of Specialized Palliative Care: A Systematic Review
Zimmermann et al.
JAMA 2008;299:1698-1709.
ABSTRACT
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Managing an Acute Pain Crisis in a Patient With Advanced Cancer: "This Is as Much of a Crisis as a Code"
Moryl et al.
JAMA 2008;299:1457-1467.
ABSTRACT
| FULL TEXT
How well do current instruments using bereaved relatives' views evaluate care for dying patients?
Mayland et al.
Palliat Med 2008;22:133-144.
ABSTRACT
The effect of the Liverpool Care Pathway for the dying: a multi-centre study
Veerbeek et al.
Palliat Med 2008;22:145-151.
ABSTRACT
Identification of Quality Indicators of End-of-Life Cancer Care From Medical Chart Review Using a Modified Delphi Method in Japan
Miyashita et al.
AM J HOSP PALLIAT CARE 2008;25:33-38.
ABSTRACT
Evidence-Based Interventions to Improve the Palliative Care of Pain, Dyspnea, and Depression at the End of Life: A Clinical Practice Guideline from the American College of Physicians
Qaseem et al.
ANN INTERN MED 2008;148:141-146.
ABSTRACT
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Evidence for Improving Palliative Care at the End of Life: A Systematic Review
Lorenz et al.
ANN INTERN MED 2008;148:147-159.
ABSTRACT
| FULL TEXT
Terminal delirium: families' experience
Namba et al.
Palliat Med 2007;21:587-594.
ABSTRACT
Having a difficult time leaving: experiences and attitudes of nurses with palliative sedation
Rietjens et al.
Palliat Med 2007;21:643-649.
ABSTRACT
Physicians' and Nurses' Preferences in Using Life-Sustaining Treatments
Carmel et al.
Nurs Ethics 2007;14:665-674.
ABSTRACT
NEGOTIATING A "GOOD DEATH": WHAT YOU NEED TO KNOW ABOUT AMERICAN HOSPITALS
Molnar
Gerontologist 2007;47:565-568.
FULL TEXT
Controlling Death: The False Promise of Advance Directives
Perkins
ANN INTERN MED 2007;147:51-57.
ABSTRACT
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Phase II Study: Integrated Palliative Care in Newly Diagnosed Advanced Non-Small-Cell Lung Cancer Patients
Temel et al.
JCO 2007;25:2377-2382.
ABSTRACT
| FULL TEXT
The Effect of Underlying Health Status on Patient or Surrogate Preferences for End-of-Life Care: A Pilot Study
Kara Zivin Bambauer and Gillick
AM J HOSP PALLIAT CARE 2007;24:185-190.
ABSTRACT
Good death in cancer care: a nationwide quantitative study
Miyashita et al.
Ann Oncol 2007;18:1090-1097.
ABSTRACT
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Spirituality, Religion, and Health
Yuen
American Journal of Medical Quality 2007;22:77-79.
Feeling like a burden to others: a systematic review focusing on the end of life
McPherson et al.
Palliat Med 2007;21:115-128.
ABSTRACT
Religiousness and Spiritual Support Among Advanced Cancer Patients and Associations With End-of-Life Treatment Preferences and Quality of Life
Balboni et al.
JCO 2007;25:555-560.
ABSTRACT
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Three Methods of Assessing Values for Advance Care Planning: Comparing Persons With and Without Dementia
Karel et al.
J Aging Health 2007;19:123-151.
ABSTRACT
End-of-Life Care: Findings From a National Survey of Informal Caregivers
Wolff et al.
Arch Intern Med 2007;167:40-46.
ABSTRACT
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The impact of conducting a regional palliative care clinical study
Currow et al.
Palliat Med 2006;20:735-743.
ABSTRACT
Palliative care for frail older adults: "there are things I can't do anymore that I wish I could . . . ".
Boockvar and Meier
JAMA 2006;296:2245-2253.
ABSTRACT
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Self-reported Practice, Confidence, and Knowledge About Palliative Care of Nurses in a Japanese Regional Cancer Center: Longitudinal Study After 1-Year Activity of Palliative Care Team
Morita et al.
AM J HOSP PALLIAT CARE 2006;23:385-391.
ABSTRACT
Preferences of the Dutch general public for a good death and associations with attitudes towards end-of-life decision-making
Rietjens et al.
Palliat Med 2006;20:685-692.
ABSTRACT
Does persistent involvement by the GP improve palliative care at home for end-stage cancer patients?
Aabom et al.
Palliat Med 2006;20:507-512.
ABSTRACT
End-of-Life Care: The Red Alert for Physicians
de Azambuja
The Oncologist 2006;11:851-852.
FULL TEXT
Factors predictive of preferred place of death in the general population of South Australia
Foreman et al.
Palliat Med 2006;20:447-453.
ABSTRACT
End-of-Life Decision Making, Organ Donation, and Critical Care Nurses
Daly
Crit Care Nurse 2006;26:78-86.
FULL TEXT
Improving the Quality of End-of-Life Care in the Pediatric Intensive Care Unit: Parents' Priorities and Recommendations
Meyer et al.
Pediatrics 2006;117:649-657.
ABSTRACT
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What matters most in end-of-life care: perceptions of seriously ill patients and their family members
Heyland et al.
CMAJ 2006;174:627-633.
ABSTRACT
| FULL TEXT
"You can't always get what you want" -- Or can you?
Teno and Dosa
CMAJ 2006;174:643-644.
FULL TEXT
Mortality after the Hospitalization of a Spouse
Christakis and Allison
NEJM 2006;354:719-730.
ABSTRACT
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"Are You at Peace?": One Item to Probe Spiritual Concerns at the End of Life
Steinhauser et al.
Arch Intern Med 2006;166:101-105.
ABSTRACT
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Providing a "Good Death": Critical Care Nurses' Suggestions for Improving End-of-Life Care
Beckstrand et al.
Am J Crit Care 2006;15:38-45.
ABSTRACT
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Parent and Physician Perspectives on Quality of Care at the End of Life in Children With Cancer
Mack et al.
JCO 2005;23:9155-9161.
ABSTRACT
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Differences between terminally ill cancer patients who died after euthanasia had been performed and terminally ill cancer patients who did not request euthanasia
Georges et al.
Palliat Med 2005;19:578-586.
ABSTRACT
Baby Doe Rules: In Reply
Kopelman
Pediatrics 2005;116:1602-1603.
FULL TEXT
Role of the doctor in relieving spiritual distress at the end of life
Pronk
AM J HOSP PALLIAT CARE 2005;22:419-425.
ABSTRACT
Palliative and End-of-Life Care for Patients With Cardiopulmonary Diseases: American College of Chest Physicians Position Statement
Selecky et al.
Chest 2005;128:3599-3610.
ABSTRACT
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Defining Cancer Patients As Being in the Terminal Phase: Who Receives a Formal Diagnosis, and What Are the Effects?
Aabom et al.
JCO 2005;23:7411-7416.
ABSTRACT
| FULL TEXT
Factors Affecting Long-Term-Care Residents' Decision-Making Processes as They Formulate Advance Directives
Lambert et al.
Gerontologist 2005;45:626-633.
ABSTRACT
| FULL TEXT
Baby Doe Rules Have Been Interpreted and Applied by an Appellate Court: In Reply
Kopelman
Pediatrics 2005;116:514-515.
FULL TEXT
Quality of Dying in the ICU: Ratings by Family Members
Mularski et al.
Chest 2005;128:280-287.
ABSTRACT
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First Rule: Choose Your Battles Wisely
Hurst
Pediatrics 2005;116:288-288.
FULL TEXT
Transitions in the lives of patients with End Stage Renal Disease: a cause of suffering and an opportunity for healing
Hutchinson
Palliat Med 2005;19:270-277.
ABSTRACT
Why are bereaved family members dissatisfied with specialised inpatient palliative care service? A nationwide qualitative study
Shiozaki et al.
Palliat Med 2005;19:319-327.
ABSTRACT
Integrated care pathway for the last days of life
Shah
Palliat Med 2005;19:351-352.
Barriers and Facilitators to End-of-Life Care Communication for Patients with COPD
Knauft et al.
Chest 2005;127:2188-2196.
ABSTRACT
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Palliative Care in the Final Days of Life: "They Were Expecting It at Any Time"
Hallenbeck
JAMA 2005;293:2265-2271.
ABSTRACT
| FULL TEXT
Medical Advance Care Planning for Persons With Serious Mental Illness
Foti et al.
Psychiatr. Serv. 2005;56:576-584.
ABSTRACT
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The Meaning Of Healing: Transcending Suffering
Egnew
Ann Fam Med 2005;3:255-262.
ABSTRACT
| FULL TEXT
Application of Community-Based Participatory Research Methods to a Study of Complementary Medicine Interventions at End of Life
Williams et al.
Complementary Health Practice Review 2005;10:91-104.
ABSTRACT
Interpersonal processes in palliative care: an attachment perspective on the patient-clinician relationship
Tan et al.
Palliat Med 2005;19:143-150.
ABSTRACT
Fear of Death
Penson et al.
The Oncologist 2005;10:160-169.
ABSTRACT
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The Evolving and Important Role of Anesthesiology in Palliative Care
Fine
Anesth. Analg. 2005;100:183-188.
ABSTRACT
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Admission to intensive care unit at the end-of-life: is it an informed decision?
Rady and Johnson
Palliat Med 2004;18:705-711.
ABSTRACT
Identifying barriers to psychosocial spiritual care at the end of life: A physician group study
Chibnall et al.
AM J HOSP PALLIAT CARE 2004;21:419-426.
ABSTRACT
Thoughts of patients with advanced heart failure on dying
Willems et al.
Palliat Med 2004;18:564-572.
ABSTRACT
Social networks and collateral health effects
Christakis
BMJ 2004;329:184-185.
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