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Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a term used to describe 2 related lung diseases: chronic bronchitis and emphysema. Chronic bronchitis is inflammation and eventual scarring of the bronchi (airway tubes). Emphysema is enlargement and destruction of the alveoli (air sacs) within the lungs. Many persons with COPD have both of these conditions.
Persons with COPD have difficulty breathing because they develop smaller air passageways and have partially destroyed alveoli. The air passageways also become clogged with mucus, a slimy substance. Smoking cigarettes is the most important risk factor and cause of COPD. About 80% to 90% of COPD cases are caused by smoking, and a smoker is 10 times more likely than a nonsmoker to die of COPD. The November 5, 2003, issue of JAMA includes an article about treatments for COPD.
SYMPTOMS OF COPD
- Chronic cough
- Increased sputum (mucus coughed from the airways)
- Shortness of breath
- Limitation of physical activity
TREATMENTS FOR COPD
- Stopping smokingextremely important to prevent worsening of the disease
- Bronchodilatorsmedications, often taken by an inhaler, that help open air passageways in the lungs
- Corticosteroidsmedications taken by inhaler to counteract inflammation in the air passages and lungs
- Oxygencan help patients with COPD who have a hard time getting enough oxygen; often stored in a portable tank
- Antibioticscan be helpful for fighting bacterial infections that make symptoms of COPD worse
FOR MORE INFORMATION
INFORM YOURSELF
To find this and other JAMA Patient Pages, go to the Patient Page link on JAMA's Web site at http://www.jama.com. A Patient Page on quitting smoking was published in the July 24/31, 2002, issue; and one on lung disease was published in the April 12, 2000, issue.
Sources: National Heart, Lung, and Blood Institute; American Lung Association; American Heart Association
The JAMA Patient Page is a public service of JAMA. The information and recommendations appearing on this page are appropriate in most instances, but they are not a substitute for medical diagnosis. For specific information concerning your personal medical condition, JAMA suggests that you consult your physician. This page may be photocopied noncommercially by physicians and other health care professionals to share with patients. Any other print or online reproduction is subject to AMA approval. To purchase bulk reprints, call 718/946-7424.
TOPIC: LUNG DISEASE
Sharon Parmet, MS, Writer;
Cassio Lynm, MA, Illustrator;
Richard M. Glass, MD, Editor
JAMA. 2003;290:2362.
RELATED ARTICLES
Contemporary Management of Chronic Obstructive Pulmonary Disease: Scientific Review
Don D. Sin, Finlay A. McAlister, S. F. Paul Man, and Nick R. Anthonisen
JAMA. 2003;290(17):2301-2312.
ABSTRACT
| FULL TEXT
Contemporary Management of Chronic Obstructive Pulmonary Disease: Clinical Applications
S. F. Paul Man, Finlay A. McAlister, Nick R. Anthonisen, and Don D. Sin
JAMA. 2003;290(17):2313-2316.
ABSTRACT
| FULL TEXT
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