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Douglas B. White, MD, MAS; Derek C. Angus, MD, MPH

JAMA. 2009;302(17):1905-1906. Published online October 12, 2009 (doi:10.1001/jama.2009.1539).

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Despite an enormous global investment in preparing for the reemergence of 2009 influenza A(H1N1), preparations proceeded largely without empirical data about the nature and severity of disease. This paucity of data is particularly problematic for clinicians in intensive care units (ICUs), who will shoulder a heavy burden for the clinical response to H1N1. In this issue of JAMA, 3 reports provide data that begin to fill this empirical void.

Domínguez-Cherit and colleagues¹ conducted an observational study of 58 patients admitted to 6 ICUs in Mexico City with H1N1-related disease during the initial outbreak in spring 2009. Kumar and colleagues² conducted a similar study of 168 critically ill patients in 38 Canadian ICUs. There were striking similarities in the main findings. Patients tended to be relatively healthy adolescents and young adults who developed a brief prodromal illness followed by rapidly . . . [Full Text of this Article]

Author Affiliations: Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Dr Angus is also a Contributing Editor, JAMA.

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