This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (26)  • Contact me when this article is cited  Related Content  • Related letters  • Similar articles in JAMA  Topic Collections  • Aging/ Geriatrics  • Informatics/ Internet in Medicine  • Internet  • Medical Practice  • Health Policy  • Law and Medicine  • Facial Plastic Surgery  • Cosmetic Surgery/ Procedures  • Alert me on articles by topic  Social Bookmarking   What's this?

Clinical and Legal Issues

Thomas T. Perls, MD, MPH; Neal R. Reisman, MD, JD; S. Jay Olshansky, PhD

JAMA. 2005;294:2086-2090.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The distribution and marketing of human growth hormone (HGH or GH) via Web sites and antiaging clinics has grown into a multimillion-dollar antiaging industry.^1-4 Despite congressional hearings warning of deceptive marketing claims and the potential health and economic dangers associated with the antiaging industry,^5-6 and statements issued by the National Institute on Aging^7-9 and the Federal Trade Commission,¹⁰ the distribution and use of GH for antiaging is now common. For example, entering the terms "HGH" and "anti-aging" into the Google search engine generated 3 410 000 hits as of September 26, 2005, many representing Web sites and clinics marketing and selling GH.

Worldwide annual sales of GH are estimated to be $1.5 to $2 billion.^{4, 11} Vance¹² has suggested that 30% of GH prescriptions in the United States are for indications not approved by the Food and Drug Administration . . . [Full Text of this Article]

Clinical Effects of GH

Author Affiliations: Geriatrics Section, Department of Medicine, Boston Medical Center and Boston University School of Medicine, Boston, Mass (Dr Perls); Department of Plastic Surgery, Baylor College of Medicine, and St Luke’s Episcopal Hospital, Houston, Tex (Dr Reisman); School of Public Health, University of Illinois at Chicago, Chicago, Ill (Dr Olshansky).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED LETTERS

Growth Hormone for "Antiaging"
Thierry Hertoghe and Suzie Schuder
JAMA. 2006;295(8):888.
EXTRACT | FULL TEXT  

Growth Hormone for "Antiaging"
Claude Dalle and Vicario Claude
JAMA. 2006;295(8):889.
EXTRACT | FULL TEXT  

Growth Hormone for "Antiaging"
Bernhard Sauter
JAMA. 2006;295(8):889.
EXTRACT | FULL TEXT  

Growth Hormone for "Antiaging"—Reply
Thomas Perls, Neal R. Reisman, and S. Jay Olshansky
JAMA. 2006;295(8):889-890.
EXTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Statement by the Growth Hormone Research Society on the GH/IGF-I Axis in Extending Health Span
Thorner
J Gerontol A Biol Sci Med Sci 2009;64A:1039-1044.
ABSTRACT | FULL TEXT  

Systematic Review: The Effects of Growth Hormone on Athletic Performance
Liu et al.
ANN INTERN MED 2008;148:747-758.
ABSTRACT | FULL TEXT  

Update in Pituitary Disease
Melmed
J. Clin. Endocrinol. Metab. 2008;93:331-338.
ABSTRACT | FULL TEXT  

Association of Total Insulin-Like Growth Factor-I, Insulin-Like Growth Factor Binding Protein-1 (IGFBP-1), and IGFBP-3 Levels with Incident Coronary Events and Ischemic Stroke
Kaplan et al.
J. Clin. Endocrinol. Metab. 2007;92:1319-1325.
ABSTRACT | FULL TEXT  

DHEA and Testosterone in the Elderly
Page et al.
NEJM 2007;356:635-637.
FULL TEXT  

Systematic Review: The Safety and Efficacy of Growth Hormone in the Healthy Elderly
Liu et al.
ANN INTERN MED 2007;146:104-115.
ABSTRACT | FULL TEXT  

Growth Hormone for "Antiaging"
Hertoghe and Schuder
JAMA 2006;295:888-888.
FULL TEXT  

Growth Hormone for "Antiaging"
Dalle and Claude
JAMA 2006;295:889-889.
FULL TEXT  

Growth Hormone for "Antiaging"
Sauter
JAMA 2006;295:889-889.
FULL TEXT  

What's new in the other general journals
Tonks
BMJ 2005;331:1045-1046.
FULL TEXT  

Drug Bust
Leslie
Sci Aging Knowl Environ 2005;2005:nf84-nf84.
ABSTRACT | FULL TEXT