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It's Not Just for Hospitals

Elizabeth A. Bancroft, MD, SM

JAMA. 2007;298:1803-1804.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Methicillin-resistant Staphylococcus aureus (MRSA) is a well-known hospital pathogen. More than 10% of bloodstream infections in hospitals are due to MRSA, and patients with MRSA have worse outcomes than those with methicillin-sensitive S aureus.^1-2 In recent years, identification of MRSA in otherwise healthy individuals in the community (community-associated MRSA) has become increasingly common.

Health care–associated and community-associated MRSA have different clinical and molecular epidemiology. Health care–associated MRSA is associated with invasive disease, health care exposure, and multidrug resistance. Community-associated MRSA has been primarily reported in young, healthy individuals with no recent health care exposure. The strains have generally been sensitive to non–-lactam antibiotics, although most have had genes for the Panton-Valentine leukocidin and other enterotoxins that may make these strains more virulent.^3-5 Health care–associated MRSA is typified by a USA100 pulse-field electrophoretic pattern, while USA300 is the most commonly reported community-associated MRSA pattern . . . [Full Text of this Article]

Author Affiliation: Los Angeles County Department of Public Health, Los Angeles, California.

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