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Frederick S. vom Saal, PhD; John Peterson Myers, PhD

JAMA. 2008;300(11):1353-1355. Published online September 16, 2008 (doi:10.1001/jama.300.11.1353).

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In this issue of JAMA, Lang and colleagues¹ report the results of the first major epidemiologic study to examine the health effects associated with the ubiquitous estrogenic chemical bisphenol A (BPA). This compound is the base chemical (monomer) used to make polycarbonate plastic food and beverage containers, the resin lining of cans, and dental sealants; it also is found in "carbonless" paper used for receipts as well as a wide range of other common household products. Based on their analysis of data from the National Health and Nutrition Examination Survey 2003-2004, Lang et al report a significant relationship between urine concentrations of BPA and cardiovascular disease, type 2 diabetes, and liver-enzyme abnormalities in a representative sample of the adult US population. This report, suggesting links between BPA and some of the most significant and economically burdensome human diseases, is based . . . [Full Text of this Article]

Author Affiliations: Division of Biological Sciences, University of Missouri, Columbia (Dr vom Saal); Environmental Health Sciences, Charlottesville, Virginia (Dr Myers).

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