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CLINICIAN'S CORNER
Heart Failure With Preserved Ejection FractionTreat Now by Treating Comorbidities
Sanjiv J. Shah, MD;
Mihai Gheorghiade, MD
JAMA. 2008;300(4):431-433.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Heart failure (HF) is a major public health problem, with a prevalence of more than 5 million cases and an incidence of 660 000 new cases per year in the United States alone.1Among patients older than 65 years, HF has become the most common discharge diagnosis and the primary cause of readmission within 60 days of discharge, resulting in estimated costs of $34.8 billion per year.1 Nearly half of all patients with HF have a preserved ejection fraction (HFPEF).2-5 Patients with HFPEF have a high all-cause mortality after hospitalization for HF: 2.9%, in-hospital mortality4; 9.5%, 60- to 90-day mortality4; 22% to 29%, 1-year mortality2-3; and 65%, 5-year mortality.2-3 These data underscore the urgent need to find ways to improve outcomes for these patients.
Unlike patients with HF and reduced ejection fraction, few large randomized controlled trials have been . . . [Full Text of this Article]
Author Affiliations: Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
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