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J Am Med Assoc. 1934;102(23):1946-1947.

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MOTION PICTURES OF BACTERIA

Since the introduction seventy-five years ago of the word Schizomycetes, the simpler bacteria have been generally regarded as unicellular plants multiplying solely by symmetrical cell division. The possibility of asymmetrical fission, with the production of daughter cells or different hereditary characters, has been denied. Reproduction by budding rather than by simple cell divisions has not been considered possible. Yet both of these bizarre types of reproduction are common, if one is to credit the photographic evidence recently reported by Wyckoff¹ of the Rockefeller Institute. To follow the finer details of bacterial growth, he studied motion pictures of pathogenic bacteria planted on agar-coated cover slips. With certain species he found that proliferation is invariably in accord with the classic nomenclature, or by an equivalent process of "coccoid division." Under certain environmental conditions, however, multiplication of many species occurs not by this conventional method but by single or multiple budding or . . . [Full Text PDF of this Article]

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