This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

WITH SPECIAL REFERENCE TO THE CEREBROSPINAL FLUID PRESSURE

JULES H. MASSERMAN, M.D.

J Am Med Assoc. 1934;102(25):2084-2086.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Following the discovery that the introduction of concentrated solutions of various salts or of dextrose into the blood stream¹ or the gastro-intestinal tract² of an experimental animal causes a diminution in its cerebrospinal fluid pressure, hypertonic solutions have been administered clinically by different routes in attempts to reduce intracranial hypertension in patients suffering from brain trauma,³ brain tumor,⁴ meningitis⁵ or brain edema with acute infections.⁶ However, more recent observations both in animals⁷ and in a small number of human beings⁸ have indicated that the initial decrease in the tension of the cerebrospinal fluid induced by these methods is superseded within from one to three hours by a persistent rise in subarachnoid pressure and an exacerbation of the initial symptoms of intracranial hypertension.

The problem, therefore, appeared to require further investigation. It is my purpose in this paper to report a study of . . . [Full Text PDF of this Article]

Author Affiliations
Resident in Neuropsychiatry, Baltimore City Hospitals BALTIMORE

From the Baltimore Psychopathic Hospital. Thanks are due to Dr. Harry Goldsmith, director of the hospital, for his cooperation in this work.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?