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SUSCEPTIBILITY AND IMMUNITYIN RELATION TO VACCINATION IN ACUTE ANTERIOR POLIOMYELITIS
JOHN A. KOLMER, M.D.
J Am Med Assoc. 1935;105(24):1956-1963.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Is it worth while to attempt vaccination against acute anterior poliomyelitis in view of the low attack rate of the disease? If so, what are the prospects of success attending such efforts since the disease is evidently caused by a virus probably multiplying on or in the susceptible anterior horn cells of the spinal cord and causing the pronounced signs of disease only when coming in contact with such cells? Is it likely that anti-body produced in human beings by vaccine of spinal cords of monkeys infected with remote passage virus will protect against the disease? If this appears possible, how should the vaccine be prepared? And if it is found possible to vaccinate human beings safely and effectively against poliomyelitis with such vaccine, how should the method be applied as a practical procedure? These and additional problems of related interest are briefly discussed herewith as the basis of my
. . . [Full Text PDF of this Article]
Author Affiliations
Professor of Medicine, Temple University School of Medicine; Director, Research Institute of Cutaneous Medicine PHILADELPHIA
From the Research Institute of Cutaneous Medicine and the Department of Medicine of Temple University.
Footnotes
Read before the Section on Pathology and Physiology at the Eighty-Sixth Annual Session of the American Medical Association, Atlantic City, N. J., June 14, 1935.
Owing to lack of space, this article has been abbreviated as it appears here. The complete article will appear in the author's reprints. A copy of the latter will be sent by the author on receipt of a stamped addressed envelop.
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