This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

J Am Med Assoc. 1938;110(24):2011-2012.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A continuous cycle of secretion and absorption of bile from the intestinal tract is apparently necessary for normal synthesis of hemoglobin. This conclusion by Hawkins and his co-workers¹ of the Department of Pathology, University of Rochester School of Medicine, is drawn from a continuation of their studies of experimental bile fistula in dogs. By the fistulas which they establish the bile is drained into the right renal pelvis. From earlier studies they found that exclusion of bile from the intestinal tract by this technic led to several abnormalities. First was the development of general osteoporosis, often leading to spontaneous fractures. Physiologic analysis showed that this abnormality of bone was caused by lack of absorption of vitamin D from the intestinal tract. The lesion in bone could be prevented by the oral administration of bile. A second abnormality of major importance was a tendency to purpura, often leading to spontaneous . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?