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HENRY ARANOW, Jr., M.D.; W. BARRY WOOD, Jr., M.D.

J Am Med Assoc. 1942;119(18):1491-1495.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Scarlet fever was identified by both Sennert and Sydenham as a separate clinical entity during the seventeenth century, but discussions of its etiology remained purely speculative until two centuries later. In 1869 Hallier¹ isolated streptococci from the blood of several patients with scarlet fever, and in the eighties W. H. Power² and Klein³ traced epidemics of the disease to milk obtained from cows with streptococcic mastitis. It is of considerable historical interest that the modern concept of the pathogenesis of scarlet fever was formulated as early as 1893. Thirty years before the classic experiments of the Dicks⁴ and Dochez,⁵ Bergé⁶ had written:

Scarlet fever is a local infection; the infectious agent which produces it is the streptococcus, in one of its virulent forms; in the common type of scarlet fever, which one might call pharyngeal, the streptococcus multiplies in the pharyngeal and tonsillar crypts . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE

From the Department of Medicine, Johns Hopkins University School of Medicine and Hospital.

Footnotes
Dr. Aranow is Harlow Brooks Scholar of the New York Academy of Medicine.

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