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A CLINICAL AND LABORATORY INVESTIGATION

J. M. ADAMS, M.D.; M. P. THIGPEN, B.S.; E. R. RICKARD, M.D.

J Am Med Assoc. 1944;125(7):473-476.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Acute upper respiratory infections, together with their complications and sequelae, vary amazingly in symptomatology, localization and severity from the common cold at one end of the series through an endless maze of possibilities to a fatal septicemia at the other end. There is no sharp line of cleavage as to classification, pathology or determinable etiology, according to Brennemann.¹ Recent progress, however, in the field of research on upper respiratory diseases has revealed two filtrable viruses, influenza A and B,² both of which may be isolated and identified. Either of these viruses may be the etiologic agent responsible for a portion of these illnesses. Moreover, reliable serologic tests have been perfected for the diagnosis of infection by these viruses.³

It has been possible to diagnose a recent epidemic of influenza among infants and children in the University of Minnesota Hospitals by isolating influenza A virus directly from unfiltered . . . [Full Text PDF of this Article]

Author Affiliations
MINNEAPOLIS

From the Department of Pediatrics, University of Minnesota Medical School, and the Influenza Laboratory, Division of Preventable Diseases, Minnesota Department of Health. The Influenza Laboratory is supported largely by funds from the International Health Division of the Rockefeller Foundation.

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