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SEARCH FOR EXTRAHUMAN SOURCES OF POLIOMYELITIS VIRUS
THOMAS FRANCIS, Jr., M.D.;
GORDON C. BROWN, Sc.D.;
LAWRENCE R. PENNER, Ph.D.
J Am Med Assoc. 1948;136(17):1088-1093.
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The best evidence of the transmission of the virus of poliomyelitis at the present time supports a person to person transfer. In spite of the logic of this thesis. based essentially on the well known fact that virus is present in the human oropharynx and intestinal tract for varying periods, one must not forget that the evidence was arrived at through processes of elimination rather than by scientifically proved experiments. Consequently, it is difficult, if not impossible, in determining the transmission of this disease. to rule out extrahuman factors completely, especially since epidemiologic observations have emphasized for years that outbreaks of poliomyelitis are correlated with seasonal influences, such as rainfall, temperature and prevalence of insects and animals.
In reviewing the literature on this subject one is impressed by the vast number of incriminations of various extrahuman factors, based at best on epidemiologic impressions gained through observations of limited accuracy, and
. . . [Full Text PDF of this Article]
Author Affiliations
Ann Arbor, Mich.
From the Department of Epidemiology and Virus Laboratory, School of Public Health, University of Michigan.
Footnotes
This investigation was aided by a grant from the National Foundation for Infantile Paralysis, Inc.
Read in the Symposium on Virus Diseases before the Section on Pathology and Physiology at the Ninety-Sixth Annual Session of the American Medical Association, Atlantic City, N.J., June 12, 1947.
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