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JOHN A. TOOMEY, M.D.

J Am Med Assoc. 1949;139(7):448-450.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The report of Byers and Moll¹ on irreversible reactions following the injection of pertussis vaccine was disturbing, since prior to it this antigen had been considered innocuous. Their observations cover a ten year period and are summarized in table 1.

In case 2, 1 of 2 siblings had epilepsy and an uncle had hydrocephalus; in case 9, 1 of 2 siblings had hydrocephalus, and in case 12, 1 patient had febrile convulsions. No cases appeared between 1940 and 1942; 1 to 4 cases were seen during each of the other years. Twelve patients had received fluid toxoid. Five had reactions after the first, 4 after the second and 6 after the third dose. Two died and 8 had irreversible cerebral damage. The dose for 4 patients was unknown. Six of the remaining 12 had been given from 40 to 45 billion, 3 had 30 billion and 2 had 10 . . . [Full Text PDF of this Article]

Author Affiliations
Cleveland

From the Department of Pediatrics, Western Reserve University, and the Department of Contagious Diseases, City Hospital.

Footnotes
Read before the Section on Pediatrics at the Ninety-Seventh Annual Session of the American Medical Association, Chicago, June 23, 1948.

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