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Harriet P. Dustan, M.D.

JAMA. 1960;172(18):2052-2056.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In the 1920's, Allen¹ recognized the importance of low-sodium diets in the treatment of hypertension, but his approach did not gain wide acceptance at that time. Twenty years later Kempner² used the rice-fruit diet, but he did not emphasize its sodium-restrictive aspects. However, subsequent use of low-sodium diets that supplied adequate protein and of rice-fruit diets which were supplemented with protein amply demonstrated that sodium restriction was the only important factor.³

Interest in low-sodium diet therapy was intense during the late 1940's. Good clinical studies, with adequate prediet control periods, established the antipressor potential of sodium restriction in a substantial proportion of hypertensive patients studied.⁴ Disappointingly, the mechanism of this antihypertensive effect was not explained, but an important background of information developed concerning physiological changes that accompany sodium restriction.

About 1951, interest in dietary treatment of hypertension began to lag, partly because few patients would follow . . . [Full Text PDF of this Article]

Author Affiliations
Cleveland

From the Research Division of Cleveland Clinic.

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