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Ralph T. Holman, Ph.D.

JAMA. 1961;178(9):930-933.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ALTHOUGH the existence of essential fatty acids (EFA) has been known for 30 years, clinical interest in these dietary substances has been slight until recently. The possible relationship of EFA to the prevention or therapy of degenerative diseases such as atherosclerosis has projected these nutrients into the first rank of medical problems and interest. Unfortunately, there are many misconceptions regarding EFA. The lag between laboratory investigation and clinical application is great. It is the aim of this article to define a few terms, correct a few false impressions and provide some background on the subject, to indicate the current status and trend of research in EFA, and to attempt the difficult extrapolation from theory to practice.

The term "essential fatty acids" has been used in several different meanings since it was first used by Burr and Burr in 1929.¹ They described a deficiency syndrome, caused by the rigid exclusion . . . [Full Text PDF of this Article]

Author Affiliations
Austin, Minn.

Professor of Physiological Chemistry, University of Minnesota, Hormel Institute.

Footnotes
The Council has authorized publication of the above report. Philip L. White, Sc.D., Secretary

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