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Baboon Renal Grafts
Claude R. Hitchcock, MD, PhD;
Joseph C. Kiser, MD;
Robert L. Telander, MD;
Edward L. Seljeskog, MD
JAMA. 1964;189(12):934-937.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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IN OCTOBER, 1960, experiments were begun testing the usefulness of the large Kenya baboon for renal grafting. Previously reported studies1,2 had indicated a physiological closeness of the Kenya baboon (Papio doguera) to man which was unusual in the animal world. Atherosclerosis had been shown to occur naturally in about 5% to 10% of older baboons,3 and electrophoretic tracings of baboon sera made in our own laboratories could be superimposed on similar tracings of human sera.
The initial studies with baboon kidney autografts and homografts were promising, and on Feb 16, 1963, the right kidney of a male baboon was implanted into the left thigh of an Indian woman suffering from terminal uremia secondary to severe pyelonephritis. The kidney functioned well for 41/2 days and served to dialyze the patient to near normal blood chemistry levels.
Report of a Case
A 65-year-old Indian woman (hospital No. A-18785) had
. . . [Full Text PDF of this Article]
Author Affiliations
Minneapolis
From the laboratories of the Minneapolis Medical Research Foundation, Inc, at Hennepin County General Hospital. Portions of these studies were conducted at the field laboratories of the Southwest Foundation for Research at Darajani, Kenya, East Africa; and also at the Southwest Laboratories for Research, San Antonio, Tex.
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