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Melvin J. Krant, MD; Margaret S. Martin, BA; Cynthia S. Brandrup, MT

JAMA. 1968;204(2):153-154.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Several recent papers have indicated that a relationship exists between the clinical course of cancer and the blood-group substance secretor factor in saliva.^1,2 An etiologic relation in 88 cases of primary bronchogenic carcinoma in the Salt Lake City area described a distinct lack of nonsecretors.³ To confirm this finding, an analysis was conducted of the frequency of this particular genetic factor occurring in a series of patients with various cancers at the Lemuel Shattuck Hospital.

Methods

In 1966, studies were made on 195 patients with cancer who admitted to the Lemuel Shattuck Hospital. Blood-group analysis and salivary-secretor status were obtained; an analysis of the clinical course of the patient was made. Five milliliters of saliva was collected; standard techniques were used for treatment of saliva and for testing it with an extract of Ulex europaeus.⁴

All nonsecretor saliva was retested with the extract and with 0 cells. . . . [Full Text PDF of this Article]

Author Affiliations
From the Oncology Division, Medical Services, Lemuel Shattuck Hospital, and Tufts University School of Medicine, Boston.

Footnotes
Reprint requests to 170 Morton St, Boston 02130 (Dr. Krant).

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