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Comment: National Cooperative StudiesAdjuvant Radiotherapy
Philip Rubin, MD
JAMA. 1968;204(3):232-233.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Renal carcinoma is not a common malignancy; it constitutes no more than 1% to 2% of all cancers. Although there are trends in the literature which suggest possible approaches to improving results, it is impossible for any one individual or even an active university hospital to mount therapeutic trials. To overcome this obstacle, a national cooperative protocol has been developed. The aim of such a controlled clinical study is to demonstrate the superiority of different types and combinations of treatment. This is done by having a number of participating institutions supply the number of patients needed. The limitation of such efforts rests on the quality of care in each clinic, whereas its strength lies in the cross-sectional representation, the standardization of treatment, and reporting of results that evolve.
During the span of the past three decades, nephrectomy has yielded a five-year survival of 31% to 50% and a ten-year figure
. . . [Full Text PDF of this Article]
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