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Gerald Burke, MD, CM; Arlene Halko, MS

JAMA. 1968;204(4):319-324.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The use of radioisotopes in the measurement of cerebral blood flow has been extensively investigated.¹ Although recent studies^2-4 involving external monitoring of intravenously administered radionuclides have been of significant value in the assessment of cerebral circulation, anatomic or regional localization of vascular lesions has proven difficult. The clinical utility of the scintillation camera in the performance of dynamic clinical studies with radioisotopes^5,6 and the recent use of short-lived radionuclides such as sodium pertechnetate Tc 99m in studies of regional blood flow⁷ suggested the feasibility of quantitating cerebral blood flow concomitant with constant visual monitoring of the passage of^99mTc through the carotid and major cerebral arteries.

Forty-four subjects without neurologic disease have been studied as controls; 15 patients with recent cerebrovascular accidents and 1 patient with an arteriovenous malformation have also been tested.

Procedure

We have recently modifiedthe scintillation camera employed,⁵ by the use . . . [Full Text PDF of this Article]

Author Affiliations
From the Radioisotope Laboratory, Division of Metabolism and Endocrinology, Department of Medicine, Michael Reese Hospital and Medical Center, Chicago.

Footnotes
Reprint requests to Michael Reese Hospital and Medical Center, 29th St and Ellis Ave, Chicago (Dr. Burke).

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