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Prophylactic vs Therapeutic Use for Transitional Cell Carcinoma of the Bladder, Group 1

Franz Buschke, MD

JAMA. 1968;206(12):2724.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Based on my personal experience with supervoltage irradiation of carcinoma of the bladder over the last 25 years¹⁹ I find external irradiation indicated as an effective primary method of choice in transitional cell carcinomas. This technique is indicated in grade IV carcinomas regardless of the degree of infiltration and in grade III tumors as long as the carcinoma has not massively invaded the muscle (stages A and B1).

It has been found to be ineffective as a curative procedure for grade I carcinoma in doses that are tolerated by the bladder wall. As a matter of fact, in some cases studied, microscopic sections of biopsy specimens taken prior to and following treatment of such carcinomas could have been exchanged.^{20, Fig 99, 100} Occasionally, however, the response to irradiation may be sufficiently great to achieve temporary regression. Treatment thus may be of a palliative value for elderly patients with . . . [Full Text PDF of this Article]

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