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Henry M. Shanoff, MD
University of Toronto

JAMA. 1970;211(12):2016.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

It is of great interest that case 2 of Kaltreider and Talal¹ showed a type 4 electrophoretic pattern and incurred premature coronary heart disease (CHD). Probably half of CHD patients with hyperlipoproteinemia will have type 2 (formerly essential hypercholesterolemia), almost half will have type 4 ("diabeticoid"), and a few, type 3 (and 5?).^2,3

Patients with CHD, as a group, are shorter and broader but weigh no more than controls.⁴ Type 2 does not relate to a specific body type or obesity. Excluding the xanthomata of the florid patients, the only external clue is the corneal arcus.⁵ In France, DeGeness⁶ has selectively associated plethoric, central obesity including a "pseudo- (or perhaps real!) hypertrophy of the parotid area" with endogenous hyperglyceridemia (of lipoprotein types 3, 4, and 5). I have been able to confirm that many CHD patients with type 4 hyperlipoproteinemia can be . . . [Full Text PDF of this Article]

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