This Article  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

JAMA. 1970;211(9):1459-1474.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Transfusions Suggested For Neonatal Disorders

Preliminary studies suggest that exchange transfusions with fresh adult blood may help sustain infants with respiratory distress syndrome until spontaneous disappearance of the hyaline membranes and associated atelectasis. Two infants with the syndrome are believed to have benefitted from the treatment.

Investigators from the University of Pennsylvania School of Medicine in Philadelphia suggested the therapy in a paper presented to the Society of University Surgeons meeting in Pittsburgh.

They said that respiratory distress syndrome (RDS) is one of three conditions in which the oxyhemoglobin dissociation curve shifts maladaptively to the left because of a drop in the level of 2,3 diphosphoglycerate (DPG) in the red cell. The other two conditions occur in patients with septic shock and in patients who have had massive bood transfusions.

Speaking for the multidisciplinary team, Leonard D. Miller, MD, explained that as DPG levels fall, there is an increase . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?