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William W. K. Zung, MD

JAMA. 1970;211(9):1532-1534.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

This presentation is a synthesis based upon knowledge and hypotheses from several areas of science in an attempt to further relate drug action and sleep disturbance. It is hoped that this approach may lead us to a rational basis for the treatment of various states of disordered sleep.

What Sleep Disturbances Are Present in Clinical Disorders?

Insomnia is a symptomatic complaint and its presence, type, and severity can only be determined individually by actual laboratory all-night studies. The main finding associated with anxiety states clinically and in the laboratory is the difficulty in falling asleep. A review of the sleep of schizophrenics indicated that sleep problems are minimal in this disorder. This is in contrast with depressive disorders in which sleep disturbance is a cardinal symptom of the illness.

The results of Fig 1 are based upon data obtained from laboratory studies using all-night electroencephalographic and electro-oculographic recordings of sleeping . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Psychiatry, Duke University Medical Center, and the Veterans Administration Hospital, Durham, NC.

Footnotes
Presented as a scientific exhibit at the 118th annual convention of the American Medical Association, New York, July 13-17, 1969.

Reprint requests to Veterans Administration Hospital, Fulton Street and Erwin Road, Durham, NC 27705 (Dr. Zung).

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