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JAMA. 1970;211(9):1536-1537.

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Twenty years after Brandt's¹ preliminary report on extracorporeal filtration of the portal blood for removal of schistosomes from rabbits and monkeys, Goldsmith and associates² performed this procedure on three patients with hepatic schistosomiasis who were undergoing splenectomy for portal cirrhosis. So successful was the filtration that the surgical team was encouraged to perform it on many other patients. By January 1968, less than two years after the first operation at the Santos Hospital, Bahia, Brazil, they were able to report more than 100 patients treated by this method in the same institution.

Patients were judged eligible for the filtration procedure only if they had hypersplenism, splenic infantilism, splenomegaly, or portal hypertension necessitating splenectomy. It was relatively easy after the spleen had been removed to insert a plastic catheter through the stump of the splenic vein into the portal vein and to divert the portal blood into an extracorporeal . . . [Full Text PDF of this Article]

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