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Echovirus as a Cause of Meningism
JAMA. 1970;212(7):1206.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Because of the prevalence of inapparent echovirus infection, the appearance of specific antibodies to the virus in the sera of patients with viral meningitis does not necessarily imply that the virus is responsible for the disease. On the other hand, isolation of virus from throats and feces of patients with viral meningitis more frequently than from normal controls in the same population at the time does give evidence supporting a causal relationship. However, epidemiological studies of this type do not establish diagnoses well enough in individual cases for study of variations in the clinical manifestations. For these reasons, isolation of echoviruses directly from the cerebrospinal fluid is to be preferred for diagnosis.
Until recently echoviruses1 have been isolated almost exclusively in monkey kidney cells. A new medium has now been added. In the current issue of the Archives of Internal Medicine, Harford and associates1 report the successful isolation of
. . . [Full Text PDF of this Article]
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