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Tobacco and HealthReport of Scottsdale Research Conference
Alister Brass, MA, BM, BCh
JAMA. 1970;213(11):1879-1880.
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The pharmacology of nicotine and other tobacco smoke fractions, and their effects on animal and human tissues, were discussed at the Second Research Conference on Tobacco and Health of the AMA-ERF, held in Scottsdale, Ariz, May 6 and 7, 1970.
The majority of the 70 papers presented dealt with animal experiments. Many were concerned with work in progress or projects about to be undertaken. A selection of the findings reported is given below.
In studies on the gastrointestinal pharmacology of nicotine, C. C. Hug, Jr., found a dose-dependent inhibition of contractile activity of both circular and longitudinal muscle in the gastric antrum, duodenum, ileum, and colon in intact dogs and monkeys. J. G. Forte reported that low levels of nicotine injected intravenously into rats had no effect on the gastric secretory response to cholinergic mediators, although high levels of nicotine either greatly reduced or completely abolished the hydrochloric acid secretory
. . . [Full Text PDF of this Article]
Author Affiliations
From the Scientific Publications Division, American Medical Association, Chicago.
Footnotes
Reprint requests to 535 N Dearborn St, Chicago 60610 (Dr. Brass).
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