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S.V.

JAMA. 1970;213(11):1889.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The repeated simplistic assertions by newscasters and concerned citizens about "air pollution," as if the air and not the lung is the victim of the polluting inhalant, may foster the notion that a simple relationship exists between pollutants and the consequent lung damage, and that much more is known about this relationship than is actually the case.

Dispelling this notion, two recent symposia on inhalation carcinogenesis¹ and pulmonary responses to inhalants² provide up-to-date information on the state of our knowledge of normal and abnormal pulmonary responses to inhalants. They also provide rare insights into the methodology of their investigations with emphasis on the choice and evaluation of their experimental models. This emphasis is most germane to the theme because it tells us about the "how's" of knowledge acquisition and the "why's" and "is-it-really-so's" of its validation—an exercise in the epistemology of science.

A model is not a mannequin. . . . [Full Text PDF of this Article]

Footnotes
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