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Julius Wolff (1836-1902) Morphogenesis of Bone
JAMA. 1970;213(13):2260.
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Julius Wolff, experimental orthopedic surgeon born in West Prussia, attended the University of Berlin, where Langenbeck, Johannes Müller, Henoch, and Frerichs were on the faculty. At the suggestion of Langenbeck, he studied the natural and aberrant formation of bone in animals, the substance of his doctoral thesis presented in 1860.1 Wolff began the practice of orthopedic surgery in Berlin, but continued his investigations into the form and function of bone on his own initiative, fostered a University affiliation, and, in 1868, became privatdocent in the department of surgery. Later Wolff was advanced to professorial status; in 1890, he was appointed director of the University Clinic for Orthopaedic Surgery which he had established, and in 1899 was advanced to Geheimrat. Earlier in his career he saw military service in the campaigns of 1864, 1866, and 1870-1871.
Wolff was not the first to consider bone as living tissue, but he focused
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