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Perry F. Harris, MD; Juan F. Sanchez, MD; Donald G. Mode, MD
Nashville, Tenn

JAMA. 1970;213(13):2271-2272.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

High doses of inorganic iodine compounds taken for extended periods will provoke iodism, chronic iodide poisoning. This is manifested by increased respiratory tract secretions, gastrointestinal symptoms such as vomiting and diarrhea, fever, skin lesions, mental disturbances, and occasionally inflammatory reactions involving the salivary glands, pharynx, and larynx. Since 1924, when Graham and Cole introduced radiopaque iodides into the blood stream for roentgenographic diagnosis, reactions to these compounds have been described. Most have been characterized by acute episodes of urticaria, laryngeal edema, cardiovascular collapse, and convulsions. Symptoms of chronic iodism have not been conspicuous.^1,2

In 1956, Sussman and Miller³ reported two cases of salivary gland enlargement occurring two days after pyelography. One showed parotid enlargement, and the other bilateral submandibular enlargement and tenderness. Both patients were afebrile, had normal renal function, and their symptoms subsided within one week. Carter reported two similar cases.⁴ Both presented . . . [Full Text PDF of this Article]

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