New anti-arrhythmic agent tested for safety, efficacy
Disopyramide shows promise as an anti-arrhythmic agent, especially in the management of arrhythmias following a myocardial infarction, according to investigators at the recent 16th annual meeting of the American College of Angiology.
In a formal presentation at the New York meeting, Robert B. Kalmansohn, MD, said disopyramide was effective in treating 30 patients with a variety of cardiac arrhythmias. All had been unresponsive to treatment with other anti-arrhythmic drugs. Only two patients had to discontinue the drug because of side-effects.
In the discussion following Dr. Kalmansohn's paper, similar findings in almost 50 patients were reported by Samuel Zoneraich, MD, an associate in cardiology at the Long Island Jewish Medical Center-Queens Hospital Center Affiliation. The results of three studies comparing disopyramide to various anti-arrhythmic agents and placebo controls also appear in a new drug application submitted to the Food and Drug Administration. According
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