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edited by Gordon T. Stewart and John P. McGovern, 196 pp, with illus, $10.50, Springfield, Ill: Charles C Thomas, Publisher, 1970.

Joseph E. Johnson III, MD, Reviewer
University of Florida Gainesville

JAMA. 1970;213(6):1042.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Penicillin remains in many ways the ideal antibiotic. The drug is bacteriocidal, and toxicity is quite low at therapeutically effective levels. However, allergic reactions have presented serious problems which were not altogether circumvented by the development of a series of new penicillins and related agents such as the cephalosporins.

Mechanisms of drug allergy remained for the most part poorly understood until the last ten years beginning with the investigations of Eisen, Parker, Levine, de Weck, and others. In this brief decade penicillin allergy has become one of the best understood forms of allergy.

Penicillin Allergy: Clinical and Immunologic Aspects is an excellent summary of the state of knowledge about this important and intriguing subject. Drawing on 13 additional contributors, all of whom have been actively involved in investigations in the area, the editors have dealt effectively with clinical complications, experimental techniques, and the immunochemical basis for the various features of . . . [Full Text PDF of this Article]

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