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S.V.

JAMA. 1970;213(8):1327-1328.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Splitting, which threatens many an eponymous disease originally thought to be a single entity, has now caught up with Conn's syndrome. Baer and asociates¹ of the Columbia-Presbyterian Medical Center contend that the difference between primary aldosteronism of adrenal cortical adenoma (aldosteronoma) and that of diffuse nonadenomatous adrenal cortical hyperplasia is sufficiently deep to justify segregating the latter as a separate disease which they choose to call pseudo-primary aldosteronism.

Nonadenomatous adrenal cortical hyperplasia with aldosteronism is not an altogether recent discovery. Although the case upon which Conn² based his original description of the disease was an aldosteronoma, he has subsequently described —as have many others—the nonadenomatous variant of the disease. But neither he nor other observers have noted significant differences between the two variants. In a recent study of 19 patients with aldosteronism before and after surgical treatment, George and co-workers³ have found that adrenal hyperplasia is as common . . . [Full Text PDF of this Article]

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