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George Morrice, MD
Newark, Ohio

JAMA. 1970;213(8):1344.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

The letter by Fedontin (212:628, 1970) describing the case of pseudotumor cerebri produced in an 18-year-old girl by hypervitaminosis A, includes the statement, "In none of the casesadults or children—has papilledema been the only finding." This patient was observed at Ohio State University Hospital.

Oliver and Havener¹ described in 1958 the case of a 14-year-old girl with bilateral papilledema, as well as loss of hair, skin changes, migratory arthritic pains, hepatomegaly and splenomegaly, hypomenorrhea, and generalized malaise. Serum vitamin A levels confirmed the diagnosis of hypervitaminosis A.

Morrice et al² in 1960 described three cases in girls 14, 15, and 16 years with diplopia, papilledema, and other symptoms suggesting brain tumor. In addition to various individual complaints, each had hypomenorrhea, alopecia, and rhagades or other marked forms of dermatosis.

Ironically, these four additional cases of papilledema due to hypervitaminosis A were all observed at . . . [Full Text PDF of this Article]

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