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Robert J. Mones, MD
New York

JAMA. 1970;214(11):2059-2060.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

This letter is in response to the letter of Drs. Sacks, Messeloff, and Schwartz in the Sept 28,1970 issue of THE JOURNAL. The letter of Dr. Sacks was related to severely disabled patients with Parkinson's disease and their response to levodopa. Many general conclusions were made, although, their information seems to be taken mainly from severely disabled patients with Parkinson's disease.

My first point is that the difficulties described in this group are not typical of patients of all ages with Parkinson's disease. Patients with mild or moderate Parkinson's disease, no matter what age, had better results than the patients who are severely disabled or have end-stage Parkinson's disease (Mones et al: New York J Med, 70:2309,1970).

Complications such as induced dyskinesias, nausea, vomiting, and psychiatric changes are all controlled by reducing the dosage of the drug. Hypotension is a less common problem but potentially dangerous . . . [Full Text PDF of this Article]

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