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Ernest H. Starling (1866-1927) The Clinician's Physiologist
JAMA. 1970;214(9):1699-1701.
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The coming of age of physiology in England half a century ago may be credited to a relatively small number of experimental scientists whose contributions usually lacked clinical application; their investigations were pursued without promise of immediate or remote pertinence to the understanding of disease. However, Ernest Henry Starling was an exception, and, although he was concerned largely with physiological studies, he has been termed "The Clinician's Physiologist."1 His inquiries into the action of the heart under stress and the mechanism of transfer of solutes and fluids in capillarytissue exchange eventually led to the understanding of the pathogenesis of cardiac failure. Other physiological studies included the discovery of secretin, the pancreatic stimulant, and the measurement of the tubular secretion of urea and sulfate in the formation of urine. Starling was especially gifted in composition and prepared such classical treatises as the Harveian oration entitled The Wisdom of the Body
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