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  Vol. 214 No. 9, November 30, 1970 TABLE OF CONTENTS
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Causes of Death in Hemophilia

Jessica H. Lewis, MD
Pittsburgh

JAMA. 1970;214(9):1707.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

The causes of death in 28 hemophiliac patients are shown in the Table. During the past 15 years, 310 hemophiliacs were seen in this laboratory and follow-up information was obtained about all except eight. Half of the 28 deaths were clearly disease related, six possibly disease related, and in the remaining eight, hemorrhage played no role. The two patients who died with serum hepatitis are included in the disease-related group as, presumably, the hepatitis virus was transmitted through plasma or fraction therapy.

Bleeding into the retroperitoneal area was the most common cause of death. In six of these patients pain and swelling developed gradually and some treatment was instituted before death. Only two of these were related to known injury. In the last two years five other patients with large retroperitoneal hematomas have been treated vigorously and survived. In these it was found necessary to keep the . . . [Full Text PDF of this Article]



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