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G. Robert Nugent, MD; Samuel M. Chou, MD
West Virginia University Medical Center Morgantown

JAMA. 1973;224(1):132.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

This letter presents preliminary information concerning a treatment of labial herpes simplex, by the topical application of ethyl ether, which has been found to consistently abort the eruptions of this lesion. We believe that the breadth of this problem justifies this pronouncement even though the series is small and somewhat personal. This painful, disfiguring, and demoralizing affliction is a recurring plague of mankind. The proposed treatment has offered the first reprieve in memory to one of the writers and immediate relief to several others in whom it has been used.

As an ether-sensitive virus, the envelope of the herpes simplex virus may be removed or the remainder of the viral structure so altered by ether that the particle becomes vulnerable to the natural host defense mechanisms. This is probably the mode of action of this agent. Chloroform has a similar effect on the virus and can be . . . [Full Text PDF of this Article]

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