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Photoinactivation of Herpes Simplex Virus Continues to Look Promising
Joseph L. Melnick, PhD, DSc;
William E. Rawls, MD
Baylor College of Medicine Houston
JAMA. 1973;226(1):79-80.
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To the Editor.—
This is in response to Rapp's comments on his unpublished work (225:459, 1973). First, herpes infections are often more than "superficial" and "uncomfortable." Even though in most cases superficial herpes simplex is not of serious consequence, recurrent herpes facialis may result in temporary disfiguration—important to persons whose public appearance constitutes their livelihood. In infants the disease may be fatal. Herpes genitalis is associated with a great deal of discomfort, and its recurrence often presents considerable anxiety and marital discord. Urinary retention requiring hospitalization may occur in some patients with herpes genitalis. Naturally, the judgment regarding the use of treatment rests partly on the degree of discomfort and disability produced by the disease.
Second, evidence is mounting that herpes genitalis may be etiologically related to cervical cancer. If the infection can be curtailed and even eliminated when it first becomes evident, the possibility exists that this cancer might
. . . [Full Text PDF of this Article]
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