This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Hugh H. Hussey, MD

JAMA. 1974;227(8):935.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Knowing that there are two types of hyperlipoproteinemia, Glueck et al¹ sought to identify hyperlipoproteinemia of children in families in which one parent had suffered myocardial infarction before the age of 50 years. The authors reasoned that such relatively early onset of coronary artery disease might well indicate familial disease and portend early development of atheromatosis in progeny.

To accomplish their purpose, the authors enlisted the assistance of local physicians (mainly pediatricians) in a search for families suitable for investigation. By this means, 70 kindreds were identified in which one parent had suffered a morbid or lethal myocardial infarction before age 50. Blood lipid and lipoprotein values were measured in 57 of the 70 afflicted parents. (Thirteen parents had died before the study was undertaken.) Similar measurements were obtained in 223 of 224 living children of the affected parents as well as in first-degree relatives in an attempt to . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?